Guide Transplants

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The surgeon will make a cut incision down the center of your chest from just below the Adam's apple to just above the navel. The surgeon will cut the breastbone sternum in half. He or she will separate the two halves of the breastbone and spread them apart to reach your heart.

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The surgeon will put tubes into your chest so that your blood can be pumped through your body by a heart-lung cardiopulmonary bypass machine while your heart is stopped and replaced. Once the blood has been completely diverted into the bypass machine and is being pumped by the machine, your doctor will remove the diseased heart.

The surgeon will sew the donor heart into place. Once your new heart is in place, he or she will connect the blood vessels carefully so there are no leaks. When your new heart is fully connected, the blood circulating through the bypass machine will be allowed back into the heart and the tubes to the machine are removed.

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Your surgeon will shock the heart with small paddles to restart the heartbeat. Wires for pacing may be put into the heart.

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Your surgeon can attach these wires to a pacemaker outside your body for a short time to pace your new heart, if needed, during the initial recovery period. The surgeon will sew the skin over the sternum back together. He or she will use sutures or surgical staples to close the incision. Tubes will be put into your chest to drain blood and other fluids from around the heart.

These tubes will be connected to a suction device to drain fluids away from the heart as it heals. After the surgery, someone will take you to the recovery room or the intensive care unit ICU and monitor you closely for several days.

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A nurse will connect you to machines that will display your electrocardiogram ECG tracing, blood pressure, other pressure readings, breathing rate, and your oxygen level. Heart transplant surgery requires a hospital stay of 7 to 14 days, or even longer. You will have a tube in your throat that connects to a breathing machine ventilator until you are stable enough to breathe on your own.

The breathing tube may stay in for a few hours up to several days, depending on your case. As you recover and start to breathe on your own, the breathing machine will be adjusted to allow you to take over more of the breathing. When you are able to breathe completely on your own and are able to cough, your doctor will remove the breathing tube. After the breathing tube is out, a nurse will help you cough and take deep breaths every 2 hours.

This will be uncomfortable due to soreness, but it is extremely important that you do this to keep mucus from collecting in your lungs and possibly causing pneumonia. Your nurse will show you how to hug a pillow tightly against your chest while coughing to help ease the discomfort. You may get pain medicine as needed, either by a nurse, or by giving it yourself by pushing a button attached to a device connected to your IV line. You may have a thin, plastic tube that goes through your nose and into your stomach to remove air that you swallow.

The tube will be taken out when your bowels are working normally.

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You will not be able to eat or drink until the tube is removed. Blood samples will be taken often to monitor your new heart, as well as other body functions. These include your lungs, kidneys, liver, and blood system. You may be on special IV medicines to help your blood pressure and your heart, and to control any problems with bleeding.

As your condition stabilizes, your doctor will gradually decrease, then stop, these medicines. If you have pacing wires in your heart, he or she will remove those too. Once your doctor removes the breathing and stomach tubes and you are stable, you may start to drink liquids. You can gradually add more solid foods as you can handle them. Your healthcare team will closely watch your anti-rejection immunosuppression medicines to make sure you are getting the right dose and the best combination of medicines.

Nurses, respiratory therapists, and physical therapists will work with you as you begin physical therapy and breathing exercises. When your healthcare provider decides you are ready, you will be moved from the ICU to a private room on a surgical unit or transplant unit. Your recovery will continue there. You can gradually increase your activity as you get out of bed and walk around for longer periods. You can eat solid foods as tolerated.

Nurses, pharmacists, dietitians, physical therapists, and other members of the transplant team will teach you what you will need to do to take care of yourself when you go home. Your healthcare team will arrange for you to go home and schedule a follow-up visit with your healthcare provider. Once you are home, it will be important to keep the surgical area clean and dry. Your doctor will give you specific bathing instructions. During a follow-up visit, your doctor will remove the sutures or surgical staples, if they were not removed before leaving the hospital.

Do not drive until your healthcare provider tells you it's OK. Other activity restrictions may apply. You will need frequent follow-up visits after transplant. These visits may include blood tests, chest X-rays, and biopsy. In a biopsy, your doctor uses a thin needle to remove tissue from the heart so he or she can examine it under a microscope. The transplant team will explain the schedule for these visits and tests.

The rehab program will continue for many months. Redness, swelling, bleeding, or drainage from the incision site or any of the catheter sites. Your healthcare provider may give you other instructions after the procedure, depending on your own case. To allow the transplanted heart to survive in your body, you will need to take medicines for the rest of your life to fight rejection.


Each person may react differently to medicines, and side effects can be serious. Your healthcare provider will tailor medicine plans to meet your needs. You may get several anti-rejection medicines at first. The doses of these medicines may change often, depending on your response.

Because anti-rejection medicines affect the immune system, you will be at higher risk for infections. It's important to keep a balance between preventing rejection and making you very susceptible to infection. Some of the infections you will be especially susceptible to include oral yeast infection thrush , herpes , and respiratory viruses. You should avoid contact with crowds and anyone who has an infection for the first few months after your surgery.

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Regular dental care also is important. Your healthcare provider or dentist may prescribe antibiotics before any dental work to help prevent infections.

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To watch for signs of rejection, you will likely get routine right heart biopsies. A biopsy is typically done once a week in the early period after a transplant, then gradually changed to monthly or longer intervals. The biopsy procedures may eventually stop. The right heart biopsy procedure may be done as an outpatient or as an inpatient if you are already in the hospital. The procedure involves a right heart catheterization. A special catheter is threaded through a vein in your neck or groin and into the right atrium of your heart.